Uranus In Cancer. Any Cancerian influence brings moodiness and changeability, and this will combine with Uranian unpredictability. This can cause problems, according to whether anxiety, concern, or indecision is shown in other areas of the chart. However, other planets and combinations can mitigate the negative influence. Originality will be present, resulting in very lively expression, either creatively or scientifically, when applied to research. There will also be a caring, humanitarian streak.